Nick Bischoff, APRN, PMHNP‑BCYour prescriber and your therapist, start to finishPrograms from $1,995
This isn’t a ketamine clinic. It’s deep inner work, with ketamine as the catalyst and integration at the center. No needles, no IV: a gentle lozenge, a quiet room, and one clinician beside you from start to finish.
Free 15-minute call. Nothing is charged until we both agree it’s a fit.
Most people picture an IV drip in a recliner. That model can help, but the medicine does most of the work and you’re left to make sense of it alone. Other practices split the work between a therapist and an outside prescriber. I built this so one person holds the whole process.
| Compared | Infusion clinic | Therapist + outside prescriber | Louisville Ketamine Therapy |
|---|---|---|---|
| Who evaluates and prescribes | Clinic physician or staff | A separate prescriber, often by video | Me, in person |
| Who’s with you during a session | Staff who check your vitals | Your therapist | Me, the whole time |
| The medicine | An IV infusion | Varies, sometimes an injection | A gentle lozenge. No needles. |
| Therapy | Separate, if at all | Yes, with the therapist | Built into every phase |
| Your medications | Usually left as they are | Handled by someone else | A plan for your whole regimen, including tapering when it makes sense |
| The goal | Symptom relief | Relief and insight | Relief, plus change that holds |
Me, in person
Elsewhere: a clinic physician or a separate prescriber
Me, the whole time
Typical clinic: staff who check your vitals
A gentle lozenge. No needles.
Typical clinic: an IV infusion
Built into every phase
Typical clinic: separate, if at all
A plan for your whole regimen, including tapering
Typical clinic: usually left as they are
Relief, plus change that holds
Typical clinic: symptom relief
Infusion clinics and therapist–prescriber teams help a lot of people, and for some they’re the better fit. If that’s you, I’ll say so on our call.
Most people who come to me have already done a lot: medication, therapy, sometimes both for years. They may understand their patterns. They just can’t seem to shift them.
You’ve tried antidepressants, therapy or both, and you still don’t feel like yourself.
The kind you can explain perfectly well and still can’t talk yourself out of.
Old experiences that still run the present, even after years of good work.
Loops and rituals that keep their grip no matter how well you understand them.
Numb, foggy or muted, and wondering who you are underneath it.
Careful tapering is a core part of my practice. It’s a goal we can plan toward, never a promise. My approach
Some heart and blood-pressure conditions, a history of psychosis or mania, pregnancy, and active substance-use concerns can mean ketamine isn’t safe for you, or that it needs a different plan. I screen every person myself, and for some conditions I’ll ask your primary care provider to clear you first.
If it isn’t right for you, I’ll tell you plainly and point you toward what might be.
Ketamine can open a window where old patterns loosen and new ones form more easily. Preparation and integration are how we use that window well.
I evaluate you myself: your health history, your medications and anything that needs a closer look. Then we get clear on what you want to work on and what the sessions will feel like, so nothing catches you off guard.
Each session is two unhurried hours in my Louisville office. You take the medicine as a lozenge, with no needles, and settle in comfortably, with an eye mask and music if you like. I stay with you from the first minute to the last.
Integration starts in the room as the medicine fades, then continues in hour-long sessions between medicine days. That’s where we turn what came up into something you can use: a pattern you can finally see, a change you actually make.
The medicine is a lozenge that dissolves in your mouth. There’s no IV and no injection. The effects come on more gradually, which leaves room to settle in and work together as the experience unfolds.
Is a lozenge as effective? Lozenges are dosed for how they absorb, and studies of sublingual ketamine show meaningful benefit. See the research
Is a lozenge as effective? Lozenges absorb differently than an injection, so they’re dosed differently. In a study of more than 1,200 people using sublingual ketamine, about 63% reported their depression improved by half or more. Head-to-head trials against injections haven’t been done, so no one can honestly say one route is better. What the research does show is that lozenges can work well, and in ketamine-assisted therapy the gentler onset leaves more room for the therapy itself.
Study: Hull et al., Journal of Affective Disorders, 2022. Open-label, without a placebo group. More on the research
Nothing is rushed, and you’re never left to figure it out alone. If anything feels like too much, tell me and we’ll work with it together.
Every program includes your evaluation, the medicine, every session with me, and integration. No separate prescriber to pay and no surprise fees.
Three medicine sessions, for seeing how you respond before committing to a full course.
Continue within 60 days and everything you paid counts toward the Full Course.
Five medicine sessions, with room for change to take hold, not just to start.
Nothing is charged until we both agree it’s a fit.
For revisiting or reinforcing the work after you’ve finished a program.
Available once you’ve completed Foundations or the Full Course.
Healing doesn’t run on a fixed schedule. If more sessions would help after your program, we’ll decide together.
If it isn’t helping, we’ll talk honestly and adjust. If you stop early, unused medicine sessions are refunded on a prorated basis.
I don’t bill insurance. You may be able to use HSA or FSA funds; check with your plan.
I’m Nick Bischoff, a board-certified psychiatric–mental health nurse practitioner. In most ketamine programs, the person who prescribes and the person who sits with you are different people, sometimes in different buildings. In mine, they’re the same person.
The person who reviewed your history, looked at your medications and chose your dose is the same person beside you when something surfaces, and the same person helping you make sense of it afterward. Nothing gets lost between providers.
I evaluate you, decide whether ketamine is safe for you, choose the dose and look at your whole medication picture.
I prepare you, stay with you through every session and do the integration work that helps change last.
Through ketamine therapy I’ve unraveled decades of unresolved trauma. In under a year I’m decreasing my antidepressants and experiencing relief I never thought possible. Not masked by medication, not positive-thinking mantras. Real, lasting healing.
Nick has helped me return to my true self. Through ketamine-assisted therapy I’m able to better live with my OCD and have learned real coping mechanisms. He is the first person who ever truly listened to me and understood me.
The medicine opens the door. The therapy is what walks through it.
Nick Bischoff, APRN, PMHNP‑BCShared with written client permission. Client experiences are individual and are not a guarantee of results. Nothing on this page is medical advice or establishes a provider–patient relationship.
of people with hard-to-treat depression responded to ketamine in a large 2023 trial, compared with 41% who responded to electroconvulsive therapy (ECT).
of people with treatment-resistant depression responded within 24 hours of a single ketamine dose, compared with 28% on an active placebo.
people who’d lived with PTSD for a median of 14 years responded to a course of ketamine, compared with 1 in 5 on an active placebo.
was the median time before relief faded after ketamine infusions given on their own. That’s why preparation and integration are built into every program.
Want to go deeper? The details and limits of each study, what the research says about lozenges and addiction, and straight answers on what it can’t tell us yet.
Read the researchStill unsure? That’s exactly what the free consultation is for.
Ketamine has been used in anesthesia for more than 50 years. At the lower doses used in therapy, with careful screening and monitoring, it’s generally well tolerated. The most common effects are temporary and fade the same day: feeling detached or dreamlike, nausea, dizziness, and a rise in blood pressure during the session.
The more serious risks linked to ketamine, like bladder problems and dependence, are mainly seen with frequent, heavy, unsupervised use, not a short, monitored course like this one. That’s why I screen everyone myself, check your vital signs, stay with you for every session, and keep all dosing in my office.
Ketamine is FDA-approved as an anesthetic. Using it for depression, anxiety, trauma or OCD is off-label. That’s common and legal in medicine, and it’s how ketamine is used in most mental health settings. The only FDA-approved form for depression is esketamine (Spravato), a nasal spray, which isn’t what I use.
This is the most common worry, and it’s one of the main reasons I’m in the room with you. The effects are time-limited, and you’re never alone with them. Much of our preparation is about how to meet whatever comes up, including the hard parts. Difficult moments are often where the most useful work happens.
You won’t be unconscious. These doses are well below what’s used for anesthesia, and you keep breathing on your own. Your sense of your body, time and surroundings can shift quite a bit, and at the peak you may not feel like talking. Letting go a little is part of the process, and I’m there the whole time. The strongest effects ease within an hour or so.
Ketamine can be misused, which is why it’s a controlled substance. In these programs the risk is kept low by design: a limited number of sessions, every dose taken in my office, and nothing sent home with you. If you have a history with substances, we’ll talk it through honestly before starting.
Usually not. Most antidepressants can be continued. A few medications, such as benzodiazepines and some mood stabilizers, can blunt ketamine’s effect, so I’ll review everything you take during your evaluation and we’ll make a plan together. Please don’t change a medication on your own to prepare.
For some people, yes. Careful tapering is a core part of my practice, and some of my clients have reduced their medications after ketamine-assisted therapy. It’s a goal we can plan toward, not a promise, and any taper happens on its own careful timeline.
A lozenge means no needles, and the effects come on more gradually, which suits the therapy side of this work. Lozenges absorb differently than an injection, so they’re dosed differently.
Studies of sublingual ketamine have shown meaningful improvements in depression and anxiety. Head-to-head trials comparing lozenges with injections haven’t been done yet, so no one can honestly say one route is better. If a lozenge isn’t the right fit for you, I’ll tell you and point you toward what is.
Spravato and infusion clinics focus on the medicine. With me, the medicine sits inside a therapy process: preparation before, me beside you during, and integration after. I handle both the prescribing and the therapy, so nothing gets lost between providers.
Most people do best with the Full Course. Five sessions give change room to take hold. Foundations is a good choice if you want to see how you respond first. If you continue within 60 days, everything you paid for Foundations counts toward the Full Course. We’ll decide together on your consultation.
Foundations is $1,995 paid in full, or two payments of $1,125. The Full Course is $3,500 paid in full, or three payments of $1,250. Both include your evaluation, the medicine, every session with me and integration. See full pricing.
I’m a self-pay practice and don’t bill insurance. You may be able to use HSA or FSA funds; check with your plan.
You’ll need someone to drive you. Plan not to drive, work or make big decisions for the rest of that day. Most people go home and rest.
I check in on how you’re doing throughout your program, not just at the end. If it isn’t helping, we’ll talk about it honestly and adjust, or look at other options. You can stop at any point. If you stop early, unused medicine sessions are refunded on a prorated basis.
It’s a 15-minute call. You tell me what’s going on and what you’ve tried. I’ll tell you honestly whether ketamine-assisted therapy makes sense for you, answer your questions, and explain next steps. There’s no charge and no obligation.
Fifteen minutes, no cost, no obligation. I take a limited number of ketamine clients each month.
Or call (502) 909‑9995
